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Silymarin is also protective against several classes of nephrotoxic drugs, in particular cisplatin and doxorubicin

A.ItamanS.Khalid-JanneyC

Extreme temperature differences can sometimes contribute to issues

Second, compared to the initial screening of VS, detailed molecular docking (especially docking that considers protein flexibility) requires a lot of computational power and is usually not suitable for the preliminary screening of ultra-large compound libraries

To translate this mechanism, we engineered an injectable hydrogel for the sequential co-delivery of cisplatin and PRMT6/USP7 inhibitors, demonstrating significantly enhanced therapeutic efficacy