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Apart from the -helical domains of the DNGs that were poorly resolved and masked out, the bound peptide, individual receptor components and heterotrimeric DNGs protein were visible in all maps, allowing robust modelling for all major components of the complexes

This test was conducted both before and after the 5-day PCPA administration period

The results were expressed as lactulose apparent permeability (Papp) calculated with the following formula: Where: C Baso = Concentration of lactulose in the basolateral compartment (mg/L)

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