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Suarez-Rivero et al., 2016

2012 Feb;35(2):454-84

We therefore assume that the reaction sequence for the reduction of roGFP2(S 2 ) requires at least a reorientation of the GSSR intermediate and that this may also be the case for other non-glutathione protein disulfide substrates

Because the mutation rate in cellular genes is thousands of times slower than that for an RNA virus, if there is a physical interaction between these two proteins as Gordon et al