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For P450 enzyme inducers, hepatocellular hypertrophy is typically characterized ultrastructurally by proliferation of smooth endoplasmic reticulum (Figure 2) that on HandEstained light microscopy sections is manifested as enlarged hepatocytes with finely granular or ground glass eosinophilic cytoplasm (Figure 3)

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It has regulatory approval in several countries for the treatment of hepatitis B, hepatitis C, and as an adjunct in cancer therapy, giving it a clinical track record that most longevity peptides lack entirely