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Additionally, overexpression of thioredoxin (Trx) has been demonstrated to inhibit the progression of insulin resistance in both type 1 and type 2 diabetes in vivo (Yamamoto et al., 2008)

Serotonin and HPA Axis BPC-157 also interacts with the serotonin system and has been shown to influence corticotropin-releasing hormone (CRH) signaling in stress models