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Abbreviations BBD: Box-Behnken design BSA: Bovine serum albumin DTNB: (5,5-dithiobis-(2-nitrobenzoic acid) GPx: Glutathione peroxidase GSH: Reduced glutathione GSSG: Oxidized glutathione LOD: Limits of detection LOQ: Limits of quantitation RSM: Response surface modeling TBuOOH: Tert-Butyl hydroperoxide TNB: Nitro-2-thiobenzoate anion WSAVA: World Small Animal Veterinary Associations References Ademi M (2023) The role of ionized water and its impact on the activity of glutathione peroxidase on rats blood serum during hyperthermic stress

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The thermal stability of 5-methyl-THF increased in skim milk due to the presence of casein and folate binding protein, and in soymilk due to the presence of phenolic antioxidant compounds 545

When left untreated, it can limit our mental and physical capacities

The compound appears to influence energy expenditure, glucose metabolism, and potentially even lipid profiles, though ongoing research continues to elucidate these mechanisms