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A change of PD-1/PD-L1 expression on peripheral T cell subsets correlates with the different stages of Alzheimer's disease

33 Although men typically consume slightly more caffeine overall, studies suggest that women, particularly those under 51 years old, may exhibit higher circulating caffeine concentrations because of slower metabolism influenced by hormonal factors, including estrogen and oral contraceptive use

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The Journals of Gerontology: Series A