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Interestingly, the closest relatives of many mtDNA-modifying enzymes, such as mtDNA polymerase, are bacteriophage proteins [94], suggesting that an infection of the mitochondrial ancestor contributed to the development of mtDNA maintenance machinery

Xiang and Oliver, 1998)

Healthcare providers should be aware of these potential side effects and monitor patients closely during treatment

46 Within orthopaedic recovery, selank's anxiolytic and neurotrophic effects may help patients maintain psychological resilience, optimize mental clarity, and participate more actively in rehabilitation protocols