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PKM2 targeting inflammation to alleviate rheumatoid arthritis has been demonstrated, and its role in regulating chondrocyte inflammation in OA has been further identified (38)

BECN1 not only regulates autophagy but also affects cystine uptake by binding to System X c , leading to inhibition of GPX4 and increased levels of lipid peroxidation, inducing ferroptosis [64, 65]

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The 0.9% benzyl alcohol concentration provides effective bacteriostatic activity without interfering with peptide stability or activity in most research applications