Despiste the wide variability in maturation timelines and functional benchmarks across different iHLO differentiation protocols 10,15,16,29,30,31 , our findings contribute a valuable reference for guiding hepatic organoid development, especially for optimizing their use in preclinical research and tailored applications such as drug metabolism and toxicology
[30] [28] Vitamin B 12 and folate status during pregnancy is associated with the increasing risk of low birth weight, [22] [31] preterm birth, [31] insulin resistance and obesity [21] [23] in the offspring
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Clinical outcomes included SRS, Clinical Global Impression Scale (CGI), Repetitive Behavior Scale (RBS-R), ABC, and OSU Autism Rating Scale (OARS-4)
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