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In REDEFINE 1 (overweight/obesity without T2D), CagriSema achieved mean weight reductions of 20.4-22.7% (vs 2.3-3.0% placebo) at 68 weeks, with 53.6% and 34.7% of patients achieving 20% and 25% weight loss, respectively

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Despite the importance of diet and weight management, however, these alone are usually not enough to prevent gout attacks in most people, who will require medications to bring their uric acid levels down to the desirable amount