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Pinealocytes and Melatonin Axis: PSCs support melatonin production and synchronization with environmental light cues, enhancing circadian rhythmicity and sleep latency

Seven of the 19 XChem hits were shown to bind to the protein, but with only a modest average peak intensity reduction of 2037% in the CPMG assay (Supplementary Table 2), suggesting that the fragments likely bound with weak (millimolar) affinities, at the very limit of the CPMG assay sensitivity

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Dietary Cholesterol Is Essential to Mast Cell Activation and Associated Obesity and Diabetes in Mice. Biochimica Et Biophysica Acta