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Study protocols should incorporate standardized dietary documentation, medication usage trajectory tracking, and continuous dynamic metabolite monitoring to control time-dependent confounding factors (161)

It is commonly selected by those who want nutrient replenishment plus antioxidant-focused wellness support with minerals like Magnesium that play a role in hydration and muscle balance

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New England Journal of Medicine, Aug 14, 2025

Holistic medicine is the best framework for this task