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This binding enhances the activity of GTPase Drp1, resulting in mitochondrial fusion and fission imbalances, mitochondrial distribution abnormalities, and mitochondrial axonal transport defects

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Lipophilic Small Molecules: Compounds like Dihexa incorporate structural modifications (such as the adamantane group on P-21) that make them sufficiently lipophilic to cross the BBB after oral absorption

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It represents the percentage of the total powder weight that is actual peptide, with the remainder being counter-ions (like acetate or trifluoroacetate from the purification process) and water