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The same dose of L-carnitine and selenium was used in the intervention group of this trial, while participants in both the intervention and control groups also received standard therapy (methimazole and beta blockers)

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This is particularly relevant in PD where sustained microglial activation in inflammasome signaling intensifies oxidative stress, disrupts synaptic integrity and accelerates dopaminergic cell loss

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Starting from day 6 we included 10 M cyclopamine to promote dorsalization