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Conclusion A series linear Ang IV analogues demonstrating improved metabolic stability and very high affinity to IRAP have been reported, e.g., the potent hexapeptides 11 (AL-11) and 12 (IVDE77) with Ki values of 7.6 and 1.7 nM, respectively, data to be compared with the Ki value of Ang IV of 62 nM in the same binding assay

We then applied the criteria for a two-way split for the with MCC and without MCC subgroups and found that all five criteria were met

Crucial biological functions such as immune response, tissue repair, hormone production, etc

Carey RM, Wang ZQ, Siragy HM

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