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In addition, we discuss therapeutic efforts, challenges in clinical translation, and future directions, including biomarker discovery, combinatorial treatment strategies, and targeted delivery systems, to enable more effective modulation of autophagy in disease

Acknowledgements The authors would like to acknowledge the facilities provided by the Department of Botany (CAS Phase VII), University of Calcutta, DBT-IPLS facility, University of Calcutta for confocal microscopy facility and IM would like to thank UGC under Government of India for CSIR-UGC NET fellowship scheme