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Hutt and colleagues (2005) developed a model that achieved a 10-fold increase in hyperplastic lesions, a 4.6-fold increase in adenomas and papilloma, a 7.25-fold increase in adenocarcinomas, and a 5-fold increase in metastatic pulmonary adenocarcinomas in mice with lifetime whole-body exposure to cigarette smoke compared with lesions in air-only sham controls

Capacity: 10 cigarettes

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