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However, it remains a preclinical compound: unapproved by the FDA, prohibited under WADAs Schedule 0 category, and without a single completed, published human trial

Structural analysis of XChem fragment hits Four key residues implicated in the binding of TIN2 TBM to TRF1 TRFH were also commonly involved in ligand binding, namely R102, E106, Q127, and R131 (Fig

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