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482 NSAIDs are involved in the prevention and treatment of AD by activating peroxisome proliferator-activated receptor gamma (PPARgamma) to reduce the neurotoxicity of microglia and monocytes and astrocyte activation

Purity: 99.99% CAS No.: 51-45-6 Formula: C 5 H 9 N 3 Molecular Weight:111.15 Storage: -20C, stored under nitrogen, away from moisture * In solvent : -80C, 6 months

406,407 Interestingly, IDH1 mutants compete for NADPH to synthesize 2-HG with other pathways that are critical for cell viability, resulting in further disruption of cellular metabolism and redox homeostasis in tumorigenesis

(PubMed) Satoskar RR, Shah SJ, Shenoy SG

It is thought that enzymes in the GI tract may break it apart before it can be absorbed