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Afr J Biotechnol 10:634863 Cuadrado A, Garcia-Fernandez LF, Gonzalez L, Suarez Y, Losada A, Alcaide V, Martinez T, Fernandez-Sousa JM, Sanchez-Puelles JM, Munoz A (2003) Aplidin induces apoptosis in human cancer cells via glutathione depletion and sustained activation of the epidermal growth factor receptor, Src, JNK, and p38 MAPK

Marchesini G, Bianchi G, Merli M et al (2003) Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial

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The area located at the C-terminus is hydrophilic due to the +2 protons, responsible for the lytic activity, for a total of +6 charges at physiological Ph (Bava et al., 2023)