glutathione s transferase p1 transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases Figure 5 from Glutathione S-transferase

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Specifically, HNF4-depleted HepG2 cells showed increased levels of methionine and cysteine but reduced Ctt, hypotaurine, taurine, and H 2 S (Fig

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The general reaction includes the formation of an unsymmetrical disulfide from the protectable protein (RSH) and GSH