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Several weeks earlier, Pfizer had independently changed the small-print booklet that accompanies all drugs to say All patients should be observed for neuropsychiatric symptoms including changes in behavior, agitation, depressed mood, suicidal ideation and suicidal behavior. (Previously the fine type had listed suicidal ideation as a rare adverse reaction.) Now, after investigating an escalating number of complaints from doctors, patients, and health-care providers, the FDA was citing 34 suicides and 420 instances of suicidal behavior in the U.S