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Two-Participant Pilot Publication A 2025 publication reported an intravenous pilot involving two adults

BPC-157 upregulates vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF) to promote angiogenesis and collagen deposition at esophageal injury sites

Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

Things will still depend on the condition, as the person could experience the effects sooner or later than usual