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Crucially, decreased IDO enzyme activity can disrupt tryptophan fermentation, affecting the gut microbiome and potentially leading to an impaired intestinal mucosal barrier, increased endotoxin translocation, and chronic inflammation

Th1/Th2 cytokine balance as a determinant of acetaminophen-induced liver injury

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This is probably due to the fact that network activity results from the synchronized activation of all excitatory synapses at the same time, and as a consequence, modulations are detected mainly by changes in the frequency of burst occurrence

5oq and Extended Data Fig