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Vagus nerve and stomach synucleinopathy in Parkinsons disease, incidental lewy body disease, and normal elderly subjects: evidence against the body-first

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Furthermore, expression or function of BBB-associated receptors and transport mechanisms can be affected leading to dysregulated molecular transport [12, 54]

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Many cardiovascular risk factors such as diabetes mellitus, hypertension and hyperlipidemia are demonstrated to stimulate the interaction of Cav-1 and eNOS, reduce nitric oxide production resulting in endothelial dysfunction and subsequently the formation of atherosclerotic lesion 41,42,43