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It is constituted by brain microvascular endothelial cells and their tight junctions, the basement membrane enveloping the endothelial cells, pericytes, and astrocytic endfeet, collectively forming a highly specialized structure that precisely regulates the exchange of substances between the central nervous system and peripheral circulation, thereby maintaining the absolute homeostasis of the cerebral microenvironment ( Figure 2 )
GSH deficiency has been associated with a more severe clinical manifestation of coronavirus
Protein-based meals compete with glutathione for absorption
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