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TABLE 1 The potential pharmacological effect and mechanism of T

In this procedure, referred to as O -GlcNAcylation, UDP-GlcNAc serves as the sugar donor, originating from glucose through the hexosamine biosynthetic pathway (HBP) 21,22,23

Naturopathic protocols may include liver-supporting nutrients like milk thistle (silymarin), B vitamins, and dietary modifications to support healthy estrogen metabolism

In cancer cells, a heightened GSH level is indispensable for scavenging excessive ROS and detoxifying xenobiotics, rendering it a potential target for cancer therapy [9]

To evaluate whether these changes will affect the metabolic profiles induced by hemin, we measured SAM and SAH levels, where SAM accumulation by hemin was reduced by DMF treatment (Fig