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Ablative surgery tries to alleviate these symptoms by creating a lesion within the internal globus pallidus, thalamus, or subthalamic nucleus to stop the overactive pathway either near the start, as in pallidotomies, or further down the line in thalamotomies [Figure 1] [74]

The key risks elevated hematocrit, estrogen conversion, lipid changes are manageable with regular labs every 6 months

Kadir A, Singh J, Rahi V, Kumar P (2022) Berberine ameliorate haloperidol and 3-nitropropionic acid-induced neurotoxicity in rats

Your provider will share personalized dosing guidance if treatment is approved, and your dose may be adjusted over time based on how you respond

et al (2020) The Renpenning syndromeassociated protein PQBP1 facilitates the nuclear import of splicing factor TXNL4A through the karyopherin 2 receptor