glutathione homeostasis Sustained dysregulation of iron and induces chronoferroptosis, a persistent ferroptotic adaptation in neuronal cells Glutathione (GSH), a powerful intracellular

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Though limited, research data proposes activation of HO-1 as a prospective approach to amplify endothelial cell longevity with HO-1 byproducts CO and bilirubin, which could postpone the emergence of diverse cardiovascular complications related to diabetes

Nat Aging (2026)