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Description

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Brain and Behavior, 3(2), 4353

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found that Lipoxin A4 could increase GPX4 levels by activating the ESR2/LPAR3/Nrf2 axis, inhibit FLS ferroptosis, thereby reducing synovial inflammation, alleviating cartilage degeneration, and mitigating pain and pathological progression in knee OA (Hu et al., 2024)

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