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Future studies should explore these complex factors to develop more effective prevention and treatment strategies for better disease management goals

First, the prolonged APP treatment time, as well as the potential long-term biological effects after APP treatment, whether beneficial or detrimental, should be explored in our future studies

Pan et al., 2022

A: A 2024 clinical trial reported 34% reduction in acne lesions at 4 weeks, 58% at 8 weeks, and 72% at 12 weeks of consistent twice-daily application