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Description

Under normal physiological conditions, Keap1, as the substrate adaptor of the E3 ubiquitin ligase complex, maintains intracellular redox balance by promoting the ubiquitination and degradation of Nrf2

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Geraghty RJ, Capes-Davis A, Davis JM, Downward J, Freshney RI, Knezevic I, Lovell-Badge R, Masters JR, Meredith J, Stacey GN, Thraves P, Vias M, Cancer Research UK (2014) Guidelines for the use of cell lines in biomedical research

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