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BPC-157 is a Schedule 4 prescription-only medicine

In rats given BPC-157, serotonin levels in the brain increase in specific regions while simultaneously decreasing in other regions, such as the hippocampus.[ref] A 2020 study found that BPC-157 reduced leaky gut syndrome by stabilizing gut permeability after NSAID use.[ref] Reducing leaky gut theoretically can affect the gut-brain axis and reduce inflammation

It has been found that MSC derived vesicles rescued the frequency of Tregs, and suppressed the expression of IL-4, GM-CSF, IFN-, IL-2, TNF-

The oral daily dose far exceeds the vitamin requirement because the normal transporter protein-mediated absorption is absent, leaving only very inefficient intestinal passive absorption

Typical ranges from individual peptide research: BPC-157 in rat studies : 10 mcg/kg most common (range: 1-1000 mcg/kg) TB-500 in mouse studies : 10-100 mcg/kg typical range Combination protocols (anecdotal clinical use only): Often 1:1 ratio by mass