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Here is the short version of what they do in the skin: So it is not just soothing for the sake of soothing

Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice

IPTW-adjusted analyses similarly found no significant differences in 90-day good outcomes (adjusted odds ratio [aOR], 0.82

While these compounds are widely discussed online, its important to note that they are not licensed for human use in the UK

Improved Sleep Quality DSIP is primarily associated with: - Increasing deep (slow-wave) sleep - Reducing night awakenings - Helping normalize disrupted sleep cycles - Potentially shortening sleep latency (time to fall asleep) Unlike sedatives, its not considered directly sedating it may support natural sleep regulation