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PPAR can upregulate genes involved in fatty acid transport, as well as the fatty acid -oxidation process related to the mitochondria and peroxisomal, to facilitate the intake, utilization, and catabolism of fatty acid (158160), and the mechanism behind this may be an increase in both number and function of mitochondria, leading to a reduction in lipid accumulation (161163)

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[DOI] [PubMed] [Google Scholar] 80.Garaci E., Palamara A.T., Di Francesco P., Favalli C., Ciriolo M.R., Rotilio G

In my early years, I'd prescribe aggressive protocols, schedule two-week follow-ups, and spend those appointments essentially being a cheerleader: "You can do this