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5-amino-1MQ, an analogue from our initial series of NNMT inhibitors with low IC 50 value (IC 50 = ~1 M;[17]), and high cell membrane permeability (Table 2), produced the greatest reduction of intracellular 1-MNA levels at a concentration of 10 M among tested inhibitors (Figure 2D)

The lack of Vitamin B12 in the diets of vegetarians has challenged researchers to develop veganic and vitamin-enriched dietary resources and supplements

Providing anti-inflammatory effects Data showed that NNMT increases collagens and inflammatory molecules, which worsen inflammation

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