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Phytosterols like -sitosterol primarily act by interfering with cholesterol-dependent cell functions and oncogenic signaling

Following xenobiotic exposure, the Nrf2/Keap1 pathway is activated, releasing Nrf2 and causing it to translocate into the nucleus where it forms a heterodimer with its partner sMAF oncogene homolog

No study has shown BPC-157 promoting tumor growth, but the concern is noted in reviews (Sikiric et al., 2014) FDA status -- added to restricted compounding list in 2024

Bonetta, 2018)

Acute nicotinamide riboside supplementation improves redox homeostasis and exercise performance in old individuals: a double-blind cross-over study