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Administered as a once-weekly subcutaneous injection, tirzepatide is available in doses ranging from 2.5 mg to 15 mg, with recommended dose escalation in 2.5 mg increments approximately every 4 weeks to minimize gastrointestinal side effects

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Pharmacol Rev 50:335356 Sipos K, Lange H, Fekete Z, Ullmann P, Lill R, Kispal G (2002) Maturation of cytosolic iron-sulfur proteins requires glutathione