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Jackson and Theiss, 2020

XC: Funding acquisition, Validation, Writing review and editing

Some microRNAs, such as miR-140, play crucial roles in cartilage homeostasis and can also be delivered into cells by cell-penetrating peptides [29,30]

Certain dog breeds, notably the Giant Schnauzer, Border Collie, and Beagle, carry a genetic predisposition for cobalamin malabsorption

Targeting inflammasome activation, inhibiting caspase-1, employing anti-inflammatory agents, and modulating the gut microbiota and bile acid metabolism represent promising avenues for developing novel treatments for this common and potentially life-threatening condition