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"I believe that the science is so strong in support of these rules and the lifesaving potential is so well established that these rules will be finalized and they will survive court challenge," Henigan told NPR

The rate of malignant transformation (often given as 1% every 5 years) is controversial because some studies do not correct for confounding factors such as smoking, while other included erythroleukoplakias, leukoplakias (diagnosed as plaque-type LP), and proliferative leukoplakia in the group of lichenoid lesions

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They have six children - three adopted and three biological

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