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These results suggested that alterations in amino acids, sphingolipids, and carbohydrates, such as L-tryptophan, sphingosine 1-phosphate, and myo-inositol, were tightly correlated with immunoinflammatory changes in the circulatory system of Chinese patients with MS

Reduced levels of GSH alter the redox state of the cell by decreasing the GSH/GSSG ratio and/or increasing ROS/RNS formation

Doses as low as 10100 g/kg have been reported to significantly improve tissue regeneration, reduce inflammation, and counteract NSAID-induced damage

The authors proposed that continual stimulation of sensory nerves during an exacerbation might have led to neuropeptide depletion, thus accounting for the decreased content

SR427248, OriGene, Rockville, MD, USA) and its negative control (SR30004, OriGene, USA) were separately transfected into 3T3-L1 cells