Meanwhile, following a prolonged period of erastin treatment, VDAC2/3 failed to be detected in the cells and such reduced expression resulted in erastin resistance (Yagoda et al., 2007)
Anim Sci
Fasting glucose and HbA1c if metabolic risk factors are present
Moreover, GPNMB has protective roles in the body by contributing to the resolution of inflammation and by inhibiting T cells activation 64,65
Overall, the majority of evidence indicates that NSW significantly contribute to increased oxidative stress and DNA damage, along with diminished DNA repair capacity and altered antioxidant defenses, potentially underlying the elevated health risks, predisposing to several chronic diseases including cancer, observed in NS-working populations 64,69,85,86