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as the disease becomes prolonged, these abnormalities appear to subside and T-cell exhaustion becomes evident (225, 254)
However, treatments with GABA, DSIP-CBBBP, and DSIP all resulted in increased struggle times compared to the model group, with CBBBP alone not showing a similar effect, indicating a differential impact on depressive-like behaviors and highlighting the potential therapeutic value of these treatments in addressing depressive symptoms associated with insomnia ( Figure 5 highlights the substantial influence of peptide treatments on the sucrose preference in mice disrupted by PCPA
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Specifically, serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured to evaluate liver function, while blood urea nitrogen (BUN) and creatinine were measured to assess kidney function
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