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We may speculate that this study provides an insight into how zinc sufficiency is important for BHMT functionality, since BHMT is a zinc dependent enzyme that catalyses the transmethylation of homocysteine to methionine in the presence of the methyl group donor betaine

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J Thorac Cardiovasc Surg 119(6):1126-32, 2000

Positive mood-related gut microbiota in a long-term closed environment: a multiomics study based on the lunar palace 365 experiment