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Its classification as a neuropeptide differentiates it from metabolic or receptor-targeted peptides, positioning DSIP within neuroregulatory research domains

In addition, we note that beginning with the FY 2022 IPPS/LTCH PPS final rule, we refer to this adjustment as the productivity adjustment rather than the MFP adjustment to more closely track the statutory language in section 1886(b)(3)(B)(xi)(II) of the Act

Li, Z., Wang, Z., Cai, S., Lin, L., Huang, G., Hu, Z., et al

J.GoebelerV.LuZ.MeixnerS

This checkpoint modulation creates permissive conditions for T cell-mediated tumor elimination and provides strong rationale for combining SFN with immune checkpoint inhibitors to overcome therapeutic resistance