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Ignoring this complexity may lead to biased clinical intervention strategies

Based on the expression, amino acid sequence, and functional mechanism of the eight mGluRs subtypes, they are divided into three groups: Group I: mGluR1 and mGluR5, Group II: mGluR2 and mGluR3, and Group III: mGluR4 and mGluR6-8 [29, 30]

When the body consumes fewer calories than it burns, physiological changes including shifts in stress hormones, electrolyte levels, and blood glucose can affect the cardiovascular system, sometimes causing a racing, fluttering, or irregular heartbeat

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