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Mobile phase composition, gradient parameters and column chemistry may significantly influence retention time and separation efficiency

doi: 10.1016/j.expneurol.2024.114797 152 WangY.WangW.YangH.ShaoD.ZhaoX.ZhangG

Laboratory investigations commonly examine 5-Amino-1MQs interaction with nicotinamide N-methyltransferase (NNMT) , an enzyme involved in cellular methylation balance and metabolic signaling networks

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Research shows NNMT overexpression is associated with various metabolic dysfunction states, so its inhibition is useful for understanding these processes