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The primary mechanism by which anti-inflammatory drugs protect mitochondria in AP is likely indirect, through the reduction of overall inflammation

Kose, D

This timing is not arbitrary

The amount of HGF inhibitor that is administered may be in the range of from about 0.1 to about 1,000 mg/kg, an preferably in the range of from about 1 to about 100 mg/kg, although as one of skill in the art will recognize, the precise amount may vary depending on one or more attributes of the drug recipient, including but not limited to: weight, overall health, gender, age, nationality, genetic history, other conditions being treated, etc., and larger or smaller doses are within the practice of this invention

Suppl 1, 2015, p