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Metabolic changes included a reduction of the usage of muscle glycogen (i.e., its carbohydrate stores) during low-intensity exercise (consistent with an increase in lipid utilization) and streamlined glucose metabolism and mitochondrial flux during high-intensity exercise, leading to reduced anaerobic ATP production (which is what leads to lactic acid build-up in muscles)

Given these cells are also CD4 + T cells like those studied by Ghergurovich et al., it is possible that production of these cytokines is impaired like their T h 1 counterparts

2017;10:1179064417695255 Sadhu SS, Wang S, Dachineni R, Averineni RK, Yang Y, Yin H, et al

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